phenol and its toxicity: a case report

نویسندگان

mahesh chand meena department of forensic medicine and toxicology, lady hardinge medical college, new delhi, india.

rahul band department of forensic medicine and toxicology, lady hardinge medical college, new delhi, india.

girish sharma department of forensic medicine and toxicology, lady hardinge medical college, new delhi, india.

چکیده

background: phenol and its derivatives like dinitrophenol and pentachlorophenol (carbolic acid) are widely used as insecticides, but they are very toxic substances. phenol is a general protoplasmic poison with corrosive local effects that denature proteins. poisoning with phenol compounds may occur by ingestion, inhalation, and absorption through skin. in this report we presented the toxicity effects of phenol and its derivatives like dinitrophenol and pentachlorophenol on humans. case report: a 27-year-old married female was found unconscious at her residence in september 2013. she was expired after hospitalization in lady hardinge medical college and its associated hospital on the same day after six hours. on examination, corrosion of skin, at angel of mouth and chin, and brown discoloration in mucosa of the esophagus were seen. histological examination showed exfoliation of esophageal mucosa and coagulative necrosis of gastric mucosa. in toxicological analyses, carbolic acid was detected. conclusion: strict precautionary measures are advised when using this compound.

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عنوان ژورنال:
iranian journal of toxicology

جلد ۸، شماره ۲۷، صفحات ۱۲۲۲-۱۲۲۴

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